The Substance
DramaHorrorSci-Fi
⭐ 7.2 / 10(418,812)
A fading celebrity takes a black-market drug: a cell-replicating substance that helps her create a younger, better version of herself.
- Rated
- R
- Runtime
- 2h 21m
- Released
- 2024
Details
Release year: 2024
Storyline
A fading celebrity takes a black-market drug: a cell-replicating substance that helps her create a younger, better version of herself.
Top credits
Directors
Writers
Cast
See all 125 credits →- Demi Moore — Elisabeth
- Margaret Qualley — Sue
- Dennis Quaid — Harvey
- Edward Hamilton-Clark — Fred
Awards
1 win & 4 nominations
See all awards →